Kolo Toure and Jerome Boateng are again ruled out of the home fixture through suspension and a knee injury respectively.
First-team coach David Platt wants to build on their achievement of lifting the FA Cup.
City will face the Potters just over 72 hours after they beat their rivals 1-0 at Wembley.
Victory for City would see them overtake Arsenal and move into third place - a scenario that, should City hold on to the position, would rule out pre-qualifying for the Champions League.
The Gunners are suddenly looking over their shoulder after they suffered a home defeat to Aston Villa yesterday and Platt said: "We've got two games to go and can take six points. If we do that we have done our job.
"We could actually get third place from Arsenal. We've got to continue to win games and continue to win trophies.
"We're delighted at this moment and quite rightly so. We should enjoy it but only until around Tuesday morning.
"We've made a big step up as regards the players that have come in, they've bedded themselves in, and as the season's gone on we've become more assured as a team.''
Stoke manager Tony Pulis must decide whether to risk key players..
Pulis gambled on the fitness of Matthew Etherington (hamstring) and Robert Huth (knee) in Saturday's defeat at Wembley, while Jermaine Pennant completed the 90 minutes despite twisting his ankle in first-half stoppage-time.
Asmir Begovic is likely to reclaim his place in goal for the Barclays Premier League clash at Eastlands, while Ricardo Fuller, Danny Higginbotham and Mamady Sidibe remain sidelined.
Highlights - Manchester City vs Stoke City (1 - 0) last meeting on Final FA Cup
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